Endocrine Abstracts

Introduction: Thymic neuroendocrine (NE) tumors associated with multiple endocrine neoplasia type 1 (MEN1) are rare, variably documented in 1–8% cases. They are malignant and aggressive tumors and form a major cause of mortality in MEN1.We report a case of thymic NE carcinoma developing rapidly after parathyroidectomy in a MEN1 patient.Case: A 45 years old man was allowed for headaches, the biology showed a hypercalcemia, a hy...

Introduction: The question of the relationship between vitamin D and cardiovascular disease is still open to debate. Recent, exciting and preliminary evidence suggests that vitamin D may play a role in the occurrence of cardiovascular events.Materials and methods: Patients of both sexes, involving 290 patients recruited between September and March, aged between 40 and 80 years, with type 2 diabetes mellitus after informed consent. We excluded patients wi...

Introduction: Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are two auto-immune diseases. They have different phenotypes and are generally believed to share a number of common etiological factors but the mechanisms leading to their dichotomy are unknown. An unusual outcome of HT is the conversion to GD.A mechanism that might be hypothesized to account for the change from HT to GD is the alteration in the biological activity of TSH recep...

Introduction: Cushing syndrome is a rare etiology of hirsutism and oligomenorrhea.Objective: Screening for Cushing’s syndrome (CS) in patients with hirsutism and oligomenorrhea.Patients and methods: A prospective study was performed from 2004 to 2012. 210 patients were admitted with the complain of hirsutism and oligomenorrhea. In order to establish the diagnosis and exclude the CS, all of them were evaluated with overnight de...

Introduction: Cushing’s syndrome is rare but severe because of his association with multiple complications and particularly increased cardiovascular factors. This complications determine a mortality rate four times higher than in general population.Objects: The aim of our study was to evalated the prevalence of cardiovascular factors in Cushing’ syndrome.Subjects and methods: Twenty-five patients with Cushing’ syndro...

Introduction: Two patients admitted for evaluation of a hypercalcemia and hypothyroidism whose etiologic diagnosis showed itself unusual.Case no. 1: A 45 years old man allowed for disorders of consciousness, vomitings and headaches, biology showed a hypercalcemia, a hypophosphoraemia, hyperPTH. The imaging revealed parathyroidal adenoma with a compressive prolactinema. Pet Scan-FDG showed a metabolic activity of the thymic cavity with a necrotic aspect, ...

Thyroglossal ductal cyst is the most common congenital cervical pathology. Abnormalities in the embryologic development and migration of the thyroid gland can result in this ectopic thyroid tissue, which may occur in the midline in any position from the base of the tongue to the mediastinum. They are rarely seen in adults. Malignant transformation of the cyst is quite rare and is encountered mostly in adults.We retrospectively reviewed two cases of thyro...

Polycystic ovary syndrome (PCOS) is the most frequent endocrinopathy in premenopausal women, and has many clinical features in common with the metabolic syndrome.Objective: The aim of our study was to evaluate the clinical characteristics of our PCOS women.Methods: Of 181 PCOS defined by the Rotterdam criteria and 90 controls were evaluated for anthropometric parameters by physical examination.Results: The PC...

Introduction: The improvement of the survival of diabetics is accompanied by the emergence of bone fragility which can directly affect, at various levels, the various components of the bone tissue leading to quantitative and qualitative anomalies. The effects of type 2 diabetes on bone are complex because they are associated with the sometimes associated disorders of nutrition, weight and age. Densitometric studies in this context are quite contradictory. We proposed to study ...

Background: Post traumatic Hypopituitarism (PTHP) is common, its prevalence is about 30%.Aim: The aim is firstly to assess the frequency and predictive factors of hypopituitarism 3 and 12 months following Brain injury (BI) in a simple of 133 victims of moderate to severe BI in two neighbors’ hospitals in the east of Algiers. Secondly is to evaluate the quality of life and neurocognitive status of this cohort.Method: Hypopituit...